James Gurney posted about Darrow's method of producing a cartoon here. Rather than me discussing Darrow's work, do link to Gurney because he offers a lot of important information along with step-by step illustrations.
Examples of Darrow's work are shown below. I have no dates for them, but his style changed little over the years. And I've taken the liberty to explain some of the jokes because many viewers of this blog are not Americans and are likely to miss the humorous points.
As an aside, the setting seems vaguely like my apartment.
Most of Darrow's situations take place indoors, so he was careful to get the perspective and other details right.
This was from about 1959 after Wright's Guggenheim museum in New York opened. Its gallery is a descending spiral while the paintings are hung in true vertical/horizontal fashion. As Darrow points out, viewing is slightly disorienting.
The setting is a business school class for secretaries (note the shorthand translations under the English words on the blackboard). The instructor is showing the girls how to avoid an amorous boss.
Here the will of a deceased rich man is being read out: guess who might get the most money.
New York traffic hasn't improved much since Darrow drew this in the late 1930s.